Linked Life Data

6129200

Source:http://linkedlifedata.com/resource/pubmed/id/6129200

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1983-2-14
pubmed:abstractText
To assess the influence of selective and nonselective beta blockers with or without ISA we evaluated the extent of pressor responses to isometric exercise in 15 hypertensive patients who had first been treated with atenolol (100 mg/day) and subsequently with mepindolol (15 mg/day) for 2 months each following placebo administration for 2 weeks. Isometric handgrip was always performed in a supine position. Blood pressure and heart rate were measured at 30% of the maximal voluntary contraction. The percentages of blood pressure increases associated with the isometric test were similar during treatment with the two beta blockers; only heart rate was significantly lower. Systolic and diastolic blood pressures showed a lower increase with mepindolol than with atenolol, but the differences were not statistically significant. In conclusion, cardioselective beta blockers without ISA and nonselective beta blockers with ISA influence systolic and diastolic blood pressure responses to a handgrip of 30% in the same way. Only heart rate shows a lower but rather small increase during the cardioselective drug treatment.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0174-4879
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Effects of different beta-receptor antagonists on handgrip in essential hypertension.
pubmed:publicationType
Journal Article