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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1983-1-7
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pubmed:abstractText |
1. Relaxations to field stimulation of sympathetic nerves were found in the guinea-pig trachea only. 2. Relaxations to field stimulation of non-adrenergic inhibitory nerves were found in the larger airways of human, monkey, guinea-pig and rabbit, but not rat. 3. Lung strips from all the mammals failed to respond to sympathetic or non-adrenergic inhibitory nerve stimulation. 4. Inhibitory beta-adrenoceptors were demonstrated in the proximal airways of all species except rabbit. 5. Of the fine airways examined, beta-adrenoceptors only were found in guinea-pig and alpha-adrenoceptors only in rabbit while rat, monkey and human tissues contained mixed populations of both receptors. 6. Adenosine is a likely candidate for the neurotransmitter in the non-adrenergic inhibitory nerves. Inhibitory receptors for adenosine were present in guinea-pig trachea although receptors for ATP are probably lacking.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0306-4492
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
189-96
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6128138-Adenine Nucleotides,
pubmed-meshheading:6128138-Adenosine,
pubmed-meshheading:6128138-Animals,
pubmed-meshheading:6128138-Catecholamines,
pubmed-meshheading:6128138-Electric Stimulation,
pubmed-meshheading:6128138-Guinea Pigs,
pubmed-meshheading:6128138-Haplorhini,
pubmed-meshheading:6128138-Humans,
pubmed-meshheading:6128138-Muscle Contraction,
pubmed-meshheading:6128138-Neurotransmitter Agents,
pubmed-meshheading:6128138-Rabbits,
pubmed-meshheading:6128138-Rats,
pubmed-meshheading:6128138-Respiratory System
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pubmed:year |
1982
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pubmed:articleTitle |
Non-adrenergic, non-cholinergic nerves in mammalian airways: their function and the role of purines.
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pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
|