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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1982-12-18
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pubmed:abstractText |
Most (greater than 90%) Escherichia coli strains isolated from children with acute non-obstructive pyelonephritis exhibit a specific type of filamentous protein appendage known as P-fimbriae. These fimbriae enable the bacterium to adhere to human uroepithelial cells by the specific recognition of and binding to a particular class of glycosphingolipids correlated to the human P-blood group antigens. In this paper a new method for the rapid and reliable identification of such P-fimbriated pyelonephritogenic bacteria is described. The method is based on particles to which the minimal glycoside receptor structure recognized by P-fimbriae is attached. Mixing these receptor-containing particles with P-fimbriated bacteria results in a strong and immediate agglutination reaction. The specificity and sensitivity of this new particle agglutination test proved to be superior to the haemagglutination assay previously used.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8126
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6127318-Agglutination Tests,
pubmed-meshheading:6127318-Bacteriuria,
pubmed-meshheading:6127318-Binding Sites,
pubmed-meshheading:6127318-Escherichia coli,
pubmed-meshheading:6127318-Fimbriae, Bacterial,
pubmed-meshheading:6127318-Glycosides,
pubmed-meshheading:6127318-Glycosphingolipids,
pubmed-meshheading:6127318-Hemagglutination Tests,
pubmed-meshheading:6127318-Humans,
pubmed-meshheading:6127318-P Blood-Group System
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pubmed:year |
1982
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pubmed:articleTitle |
Rapid identification of P-fimbriated Escherichia coli by a receptor-specific particle agglutination test.
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pubmed:publicationType |
Journal Article,
Comparative Study
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