Linked Life Data

6126163

Source:http://linkedlifedata.com/resource/pubmed/id/6126163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-10-29
pubmed:abstractText
The effects of a single therapeutic dose of sympathomimetics, adrenaline, ethylphenylephrine, isoprenaline and terbutaline on venous return and other peripheral vascular beds were compared in dogs subjected to controlled cardiac output. The intra-aortic administration of adrenaline (1 microgram/kg) produced increases in femoral arterial pressure (FAP), left auricular outflow (LAO) and superior vena-caval flow (S-VCF), while no significant change was observed in inferior vena-caval flow (I-VCF) and femoral venous pressure. Ethylphenylephrine (0.4 mg/kg), a selective alpha-adrenoceptor stimulant, showed almost the same pattern of change but of smaller magnitude as adrenaline, though the duration of the effect was longer. Isoprenaline (1 microgram/kg) showed decreases in FAP and LAO, and marked increases in S-VCF and I-VCF. Terbutaline (20 microgram/kg), a beta2-adrenoceptor stimulant, showed no significant effect on LAO, though other parameters changed with the same pattern produced by isoprenaline.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0301-4533
pubmed:author
pubmed:issnType
Print
pubmed:volume
257
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-62
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Comparison of effects of adrenaline, ethylphenylephrine, isoprenaline and terbutaline on the vascular system.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't