Linked Life Data

6125242

Source:http://linkedlifedata.com/resource/pubmed/id/6125242

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-10-21
pubmed:abstractText
The acetoacetyl-CoA thiolase activity was estimated in subcellular fractions isolated from the cerebral hemispheres, the optic lobes and the cerebellum of the chick between the 20th day of embryonic life and the 30th day of postnatal maturation. Acetoacetyl-CoA thiolase is located both in mitochondria and microsomes of the chick brain. Mitochondrial enzyme activity remains high between the 20th day of embryonic life and the 2nd or the 4th day after hatching, depending on the considered brain area. It then decreases until 30 days after hatching. Cytoplasmic thiolase activity remains unchanged during pre- and postnatal development in the cerebral hemispheres; it increases during the same time in the optic lobes. In the cerebellum, cytoplasmic thiolase activity develops in the same way as in mitochondria. The regulation of ketone body utilization by the developing chick brain widely differs from that by the mammalian brain. In the chick, 3-hydroxybutyrate is nearly the single ketone body utilized by the brain. It is converted into acetyl-CoA in the mitochondria and cytoplasm of the chick brain through two exactly parallel pathways involving the participation of the same enzymes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
241
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Activity of acetoacetyl--CoA thiolase and regulation of ketone body metabolism in the brain of the developing chick.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't