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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8294
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pubmed:dateCreated |
1982-9-17
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pubmed:abstractText |
A simple steroid trial was conducted to assess whether 31 patients with chronic airflow obstruction would benefit from oral steroid therapy. Peak expiratory flow (PEF), forced expired volume in 1 s (FEV1), and ratio of FEV1, to forced vital capacity (FVC) were monitored during a 6-month period (when patients were on maximum bronchodilator therapy), after 2 weeks on placebo and after 2 weeks on prednisolone 30 mg daily. Patients also measured that PEF at home thrice daily. None had a significant degree of steroid reversible airflow obstruction. The preliminary observation period (of at least 3 months) is important to prevent an improvement being attributed to steroids, when it has in fact occurred spontaneously or is the result of bronchodilator therapy or cessation of smoking.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
345-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6124757-Administration, Oral,
pubmed-meshheading:6124757-Aged,
pubmed-meshheading:6124757-Chronic Disease,
pubmed-meshheading:6124757-Clinical Trials as Topic,
pubmed-meshheading:6124757-Double-Blind Method,
pubmed-meshheading:6124757-Female,
pubmed-meshheading:6124757-Forced Expiratory Volume,
pubmed-meshheading:6124757-Humans,
pubmed-meshheading:6124757-Lung Diseases, Obstructive,
pubmed-meshheading:6124757-Male,
pubmed-meshheading:6124757-Middle Aged,
pubmed-meshheading:6124757-Peak Expiratory Flow Rate,
pubmed-meshheading:6124757-Prednisolone,
pubmed-meshheading:6124757-Vital Capacity
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pubmed:year |
1982
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pubmed:articleTitle |
Assessment of steroid responsiveness in patients with chronic airflow obstruction.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|