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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8289
|
pubmed:dateCreated |
1982-8-26
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pubmed:abstractText |
In a randomised controlled trial the effect of intermittent bolus injection of triglycyl lysine vasopressin (terlipressin 'Glypressin') (2 mg that 6-hourly), an analogue of vasopressin, was compared with that of a constant peripheral intravenous infusion of vasopressin (0.4 units/Min) in the initial management of bleeding oesophageal varices in nineteen patients. Failure of vasopressin therapy was defined as continued bleeding of sufficient severity to necessitate the passage of a Sengstaken tube. Bleeding was controlled in 70% of patients treated with glypressin but in only 9% of patients given vasopressin. The glypressin group required significantly less blood after randomisation than the vasopressin group. Because of its efficacy, lack of side-effects, and ease of administration, glypressin appears to be valuable in the management of bleeding varices.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
10
|
pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
66-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:6123808-Adult,
pubmed-meshheading:6123808-Aged,
pubmed-meshheading:6123808-Clinical Trials as Topic,
pubmed-meshheading:6123808-Esophageal and Gastric Varices,
pubmed-meshheading:6123808-Female,
pubmed-meshheading:6123808-Gastrointestinal Hemorrhage,
pubmed-meshheading:6123808-Humans,
pubmed-meshheading:6123808-Infusions, Parenteral,
pubmed-meshheading:6123808-Lypressin,
pubmed-meshheading:6123808-Male,
pubmed-meshheading:6123808-Middle Aged,
pubmed-meshheading:6123808-Random Allocation,
pubmed-meshheading:6123808-Vasopressins
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pubmed:year |
1982
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pubmed:articleTitle |
Controlled trial of terlipressin ('Glypressin') versus vasopressin in the early treatment of oesophageal varices.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|