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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8278
|
pubmed:dateCreated |
1982-7-19
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pubmed:abstractText |
In a double-blind crossover study of the effects of the antigonadotropin danazol on pain and nodularity in 28 women with cyclical mastalgia danazol was given at doses of 200 mg/day and 400 mg/day, and the responses were assessed both subjectively and objectively. Danazol caused a significant and progressive decrease in breast pain and nodularity when compared with placebo. Symptoms responded more quickly with the 400 mg/day dose of danazol than with the 200 mg dose, but the larger dose also caused greater side-effects. Danazol is a useful addition to the range of antihormones that can be used to suppress the symptoms of severe hormone-related benign breast disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
928-30
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6122770-Adult,
pubmed-meshheading:6122770-Breast Diseases,
pubmed-meshheading:6122770-Clinical Trials as Topic,
pubmed-meshheading:6122770-Danazol,
pubmed-meshheading:6122770-Dose-Response Relationship, Drug,
pubmed-meshheading:6122770-Double-Blind Method,
pubmed-meshheading:6122770-Female,
pubmed-meshheading:6122770-Gonadotropins,
pubmed-meshheading:6122770-Humans,
pubmed-meshheading:6122770-Pain,
pubmed-meshheading:6122770-Pregnadienes,
pubmed-meshheading:6122770-Random Allocation
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pubmed:year |
1982
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pubmed:articleTitle |
Controlled trial of the antigonadotropin danazol in painful nodular benign breast disease.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|