Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1982-4-20
|
| pubmed:abstractText |
Sixty-seven Macaca rhesus monkeys were inoculated with 2 mutants and 3 virulent strains of tick-borne encephalitis (TBE) virus including strains isolated from patients with a chronic form of TBE. A model of the clinical course of acute, subacute, and chronic encephalitis was produced by intracerebral inoculation and that of asymptomatic infection was produced by subcutaneous inoculation [with or without administration of cyclophosphane (CP)]. Virus persistence developed after inoculation with all the strains, after non-fatal encephalitis and inapparent infection irrespective of CP administration. In monkeys recovering from encephalitis the virus persisted for at least 783 days. After asymptomatic infection, it persisted for 302 days; neither virus nor virus-specific antigen was detected at 356, 367, and 620 days.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0001-723X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
337-43
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6120634-Animals,
pubmed-meshheading:6120634-Chronic Disease,
pubmed-meshheading:6120634-Encephalitis, Tick-Borne,
pubmed-meshheading:6120634-Encephalitis Viruses, Tick-Borne,
pubmed-meshheading:6120634-Macaca,
pubmed-meshheading:6120634-Macaca mulatta,
pubmed-meshheading:6120634-Mutation,
pubmed-meshheading:6120634-Time Factors
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Persistence of tick-borne encephalitis virus in monkeys. I. Features of experimental infection.
|
| pubmed:publicationType |
Journal Article
|