Linked Life Data

6120402

Source:http://linkedlifedata.com/resource/pubmed/id/6120402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8271
pubmed:dateCreated
1982-4-22
pubmed:abstractText
A five-year study of all newly diagnosed cases of chronic active hepatitis (CAH) from a defined population of 404,000, in which the internationally accepted diagnostic criteria were applied, is reported. A putative aetiological agent was identified in all but 14 (23%) of 61 cases. Alcohol (26%) and hepatitis B (20%) were the commonest aetiological factors. The incidence of CAH was 3 per 100,000 per year. Patients were often elderly, mean age 56, with a third aged over 65. A third were symptom-free at diagnosis, and the disease was biochemically or histologically severe in only a few. 9 of 61 (15%) fulfilled the criteria for treatment used in the Mayo Clinic trials. Even after exclusion of those with CAH unresponsive to corticosteroids (i.e., where hepatitis B, drugs, alcohol are involved in the aetiology) and widening of the criteria, only 7 of the remaining 31 (23%) are likely to benefit from corticosteroids. The variety of aetiological agents, spectrum of clinical features, and range of disease severity are very different in an unselected group from those reported from specialised referral centres.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
550-2
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Chronic active hepatitis: the spectrum of disease.
pubmed:publicationType
Journal Article