Linked Life Data

6120137

Source:http://linkedlifedata.com/resource/pubmed/id/6120137

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1982-4-22
pubmed:abstractText
Melanoma and neuroblastoma are diagnosed by their clinical and histological features, including evidence of melanogenesis and neural differentiation respectively, by tumour cells. These criteria are occasionally inadequate. Melanoma and neuroblastoma are derived from a system of cells characterized by the content, precursor uptake and decarboxylation of particular amines (APUD cells). Neurone specific enolase (NSE) has been proposed as a specific marker for neural elements and APUD cells. Immunohistochemical cytoplasmic and fibrillary localization of this enzyme was demonstrated in formalin-fixed, paraffin-processed sections of melanoma and neuroblastoma, constituting and additional aid to the identification of these tumours. The demonstration of an enzyme of the glycolytic pathway within tumour cells has implications following the effects of anti-tumour agents and these are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0309-0167
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-92
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Neurone specific enolase: an aid to the diagnosis of melanoma and neuroblastoma.
pubmed:publicationType
Journal Article