Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1982-3-13
pubmed:abstractText
The quantal transmitter release of tetanus (TeTx) and botulinum A (BoTx) toxin paralyzed mouse diaphragms was studied. The very low release probability could be enhanced by increasing the frequency of nerve stimulation to 50 Hz or by the application of 4-aminopyridine. In the BoTx-muscles the endplate potentials were strongly coupled to the stimuli with synaptic delays similar to unpoisoned terminals. In contrast, in the TeTx-muscles large variations in the delay of release of quanta in response to stimulation were observed. From these findings it is suggested that TeTx and BoTx act at different sites of the depolarization-transmitter release process.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
307-11
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Different effects of botulinum A toxin and tetanus toxin on the transmitter releasing process at the mammalian neuromuscular junction.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't