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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
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|
pubmed:dateCreated |
1982-1-9
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|
pubmed:abstractText |
The effect of H1 and H2 receptor-blocking agents on antibody-dependent cell-mediated cytotoxicity (ADCC) was studied. The H1 receptor-blocker clemastinum and the H2 receptor blocker cimetidine dose-dependently inhibited the antibody-dependent cytotoxic activity of normal human peripheral blood mononuclear cells on chicken erythrocytes. The inhibition cannot be explained either by a direct toxic effect on effector cells or by blocking of Fc receptors. The possible involvement of histamine receptor-bearing effector cells in human ADCC is suggested.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0300-9475
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
13
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
361-6
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|
pubmed:dateRevised |
2004-11-17
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|
pubmed:meshHeading |
pubmed-meshheading:6117941-Animals,
pubmed-meshheading:6117941-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:6117941-Chickens,
pubmed-meshheading:6117941-Cimetidine,
pubmed-meshheading:6117941-Clemastine,
pubmed-meshheading:6117941-Erythrocytes,
pubmed-meshheading:6117941-Histamine,
pubmed-meshheading:6117941-Histamine H1 Antagonists,
pubmed-meshheading:6117941-Histamine H2 Antagonists,
pubmed-meshheading:6117941-Humans,
pubmed-meshheading:6117941-Monocytes
|
|
pubmed:year |
1981
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|
pubmed:articleTitle |
Effect of histamine receptor blocking on human antibody-dependent cell-mediated cytotoxicity.
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|
pubmed:publicationType |
Journal Article
|
