Linked Life Data

6116630

Source:http://linkedlifedata.com/resource/pubmed/id/6116630

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1981-12-21
pubmed:abstractText
A model of the immobilization stress aided to study the main characteristics of dexametasone-binding and transcortin-like receptors in the liver and heart cytosol, the level of endogenous corticosterone, induction of the glucocorticoid--dependent liver enzyme tyrosine aminotransferase (TATF), and amount of a number of metabolites. The study revealed disturbances of the receptor binding and cellular metabolism during the stress. A sharp increase of endogenous glucocorticoids in blood and tissues along with inhibition of the glucocorticoid receptor binding in organs and of the TATF activity, exhaustion of cellular contents of glucose and cholesterine, a decrease in the protein amount, increasing level of urine in blood and tissues as well as a considerable hyposodiumemia indicate transition of the stress from the compensated phase into the decompensated one.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0015-329X
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1258-64
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
[Glucocorticoid receptors and metabolic disorders of the liver and heart following immobilization].
pubmed:publicationType
Journal Article, English Abstract