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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-10-29
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pubmed:abstractText |
Lymph nodes of 5 cases with non-specific lymphadenitis and of 4 cases with dermatopathic lymphadenitis were examined by the peroxidase anti-peroxidase (PAP) method and by immunoelectron microscopy using monospecific antibody against nervous system specific S-100 protein. S-100 protein was detected in dendritic shaped cells of the thymus-dependent area of non-specific lymphadenitis. The paracortical area of dermatopathic lymphadenitis showed a marked accumulation of S-100 protein-containing dendritic shaped cells. Immunoelectron micrographs revealed that S-100 protein-containing dendritic shaped cells of both non-specific and dermatopathic lymphadenitis corresponded to interdigitating reticulum cells (IRC). The detection of S-100 protein in the nucleus and on the cytoplasmic and nuclear membrane suggested that IRCs themselves synthesized S-100 protein. S-100 protein is a very useful cell marker for the identification of IRC in the lymphoid tissue.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0340-6075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
125-35
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6115501-Cell Nucleus,
pubmed-meshheading:6115501-Cytoplasm,
pubmed-meshheading:6115501-Humans,
pubmed-meshheading:6115501-Immunoenzyme Techniques,
pubmed-meshheading:6115501-Lymph Nodes,
pubmed-meshheading:6115501-Lymphadenitis,
pubmed-meshheading:6115501-Microscopy, Electron,
pubmed-meshheading:6115501-Mononuclear Phagocyte System,
pubmed-meshheading:6115501-Nerve Tissue Proteins,
pubmed-meshheading:6115501-Nuclear Envelope,
pubmed-meshheading:6115501-S100 Proteins
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pubmed:year |
1981
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pubmed:articleTitle |
Immunohistochemical and immunoelectron microscopic localization of S-100 protein in the interdigitating reticulum cells of the human lymph node.
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pubmed:publicationType |
Journal Article
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