Linked Life Data

6114324

Source:http://linkedlifedata.com/resource/pubmed/id/6114324

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8241
pubmed:dateCreated
1981-9-25
pubmed:abstractText
Histomorphometry has been applied to trabecular bone samples obtained post-mortem from young and old women without known bone disease and to bone biopsy specimens from patients with postmenopausal osteoporosis. Bone volume was significantly lower in the old than young controls and significantly lower again in the osteoporotics. The loss of bone with age associated with a rise in surface resorption but no change in forming surface, and the further loss in osteoporotics was associated with a further rise in resorption and a small non-significant fall in forming surfaces. It is suggested that trabecular bone volume is determined by the relation between total forming surface on the one hand and percent surface resorption on the other, and this relationship is expressed in mathematical terms. Age-related bone loss (simple osteoporosis) in women is accounted for by increased resorption, and accelerated osteoporosis is mainly due to a further increase in resorption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
277-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Bone formation and resorption as the determinants of trabecular bone volume in postmenopausal osteoporosis.
pubmed:publicationType
Journal Article