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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1981-8-20
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pubmed:abstractText |
The mammalian testes have several mechanisms to propel the nonmotile spermatozoa in the seminiferous tubules through the rete testis into the epididymis. These include (a) contractions of the testicular capsule and the seminiferous tubules and (b) fluid flow through the excurrent ducts resulting from active transport of fluids and electrolyte into the seminiferous tubules from the extracellular space. The efflux of fluids and sperm from the testis appears to closely parallel spermiation. An increased output of fluid may result from prostaglandins (PGF2 alpha) and possibly oxytocin (not all species respond to oxytocin) as a result of capsular contractions compressing and expelling the fluid from the tubules. Seminiferous tubular contractions do not result from nervous stimulation but are linked to PGs and cyclic nucleotide generation. They are regulated to some extent by androgens and the lesser response of the tubules to 5 alpha-dihydrotestosterone compared to testosterone can be explained by their interaction with androgen binding protein and their action on phospholipase A2 activity for PG synthesis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androgen-Binding Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic GMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Dihydrotestosterone,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyprostaglandin Dehydrogenases,
http://linkedlifedata.com/resource/pubmed/chemical/MSH Release-Inhibiting Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipases A,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipases A2,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandins,
http://linkedlifedata.com/resource/pubmed/chemical/Testosterone,
http://linkedlifedata.com/resource/pubmed/chemical/Vasotocin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0148-5016
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-94
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6113819-Androgen-Binding Protein,
pubmed-meshheading:6113819-Animals,
pubmed-meshheading:6113819-Calcium,
pubmed-meshheading:6113819-Cyclic AMP,
pubmed-meshheading:6113819-Cyclic GMP,
pubmed-meshheading:6113819-Cyclooxygenase Inhibitors,
pubmed-meshheading:6113819-Dihydrotestosterone,
pubmed-meshheading:6113819-Humans,
pubmed-meshheading:6113819-Hydroxyprostaglandin Dehydrogenases,
pubmed-meshheading:6113819-MSH Release-Inhibiting Hormone,
pubmed-meshheading:6113819-Male,
pubmed-meshheading:6113819-Muscle Contraction,
pubmed-meshheading:6113819-Phospholipases A,
pubmed-meshheading:6113819-Phospholipases A2,
pubmed-meshheading:6113819-Progesterone,
pubmed-meshheading:6113819-Prostaglandins,
pubmed-meshheading:6113819-Seminiferous Tubules,
pubmed-meshheading:6113819-Species Specificity,
pubmed-meshheading:6113819-Sperm Transport,
pubmed-meshheading:6113819-Testis,
pubmed-meshheading:6113819-Testosterone,
pubmed-meshheading:6113819-Vasotocin
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pubmed:year |
1981
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pubmed:articleTitle |
Contractility of seminiferous tubules as related to sperm transport in the male.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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