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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1981-4-13
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pubmed:abstractText |
A simple, nonsurgical means of differentiating biliary atresia (BA) from neonatal hepatitis has remained elusive. To determine its diagnostic usefulness, serum gamma-glutamyl transpeptidase (GGTP) levels were measured prospectively in 17 infants (aged 5 to 16 weeks) admitted consecutively to rule out BA. Seven patients were found to have BA, seven had neonatal hepatitis (NH), and three had alpha 1-antitrypsin (A1A) deficiency. The mean maximal GGTP level in those patients with NH (183 +/- 54 IU/L) was significantly lower than that found in patients with BA (760 +/- 492 IU/L) or A1A deficiency (1,725 +/- 921 IU/L). In the 14 patients without A1A deficiency, a serum GGTP level greater than 300 IU/L correctly identified six of seven patients with BA, while a GGTP level less than 300 IU/L correctly identified seven of seven patients with NH, although including one false-negative finding, in a patient with choledochal cyst and BA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-922X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
135
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
134-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6110334-Bile Ducts,
pubmed-meshheading:6110334-Clinical Enzyme Tests,
pubmed-meshheading:6110334-Diagnosis, Differential,
pubmed-meshheading:6110334-Female,
pubmed-meshheading:6110334-Hepatitis,
pubmed-meshheading:6110334-Humans,
pubmed-meshheading:6110334-Infant,
pubmed-meshheading:6110334-Liver,
pubmed-meshheading:6110334-Male,
pubmed-meshheading:6110334-Prospective Studies,
pubmed-meshheading:6110334-alpha 1-Antitrypsin Deficiency,
pubmed-meshheading:6110334-gamma-Glutamyltransferase
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pubmed:year |
1981
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pubmed:articleTitle |
Use of gamma-glutamyl transpeptidase in the diagnosis of biliary atresia.
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pubmed:publicationType |
Journal Article
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