Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5800
pubmed:dateCreated
1981-4-24
pubmed:abstractText
The HLA-A and -B antigens, encoded in the major histocompatibility complex, are transmembrane proteins whose carboxy termini project inwards from the cell membrane. The intracellular region of the HLA-B7 antigen is known to include two glutamine residues. We have used guinea pig transglutaminase to show that in vitro the enzyme couples amines specifically to glutamine residues in the carboxy-terminal region of the HLA-B7 and -A2 antigens. The specificity of this reaction has an immediate practical significance, but may also have a wider biological interest.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
289
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
819-21
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Transglutaminase modifies the carboxy-terminal intracellular region of HLA-A and -B antigens.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.