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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1981-4-13
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pubmed:abstractText |
The maternal and fetal effects of aminophylline on hemodynamics and acid-base and blood gas balances were evaluated by 11 infusions to four chronically catheterized sheep at 114-142 days' gestation. Maternal and fetal arterial blood samples were drawn for baseline determination at 15-minute intervals. Mean maternal and fetal pH levels and heart rates increased significantly. Respiratory alkalosis was indicated by a concomitant fall in mean maternal carbon dioxide pressure. We conclude that aminophylline infusion (5.6 mg/kg of body weight/15 min) to pregnant sheep may cause maternal and fetal tachycardia and alkalosis, with a possible increase in uterine blood flow, but no changes in fetal blood gas status or blood pressure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0020-7292
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-23
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6109660-Acid-Base Equilibrium,
pubmed-meshheading:6109660-Aminophylline,
pubmed-meshheading:6109660-Animals,
pubmed-meshheading:6109660-Blood Pressure,
pubmed-meshheading:6109660-Carbon Dioxide,
pubmed-meshheading:6109660-Female,
pubmed-meshheading:6109660-Fetus,
pubmed-meshheading:6109660-Heart Rate,
pubmed-meshheading:6109660-Hemodynamics,
pubmed-meshheading:6109660-Oxygen,
pubmed-meshheading:6109660-Pregnancy,
pubmed-meshheading:6109660-Regional Blood Flow,
pubmed-meshheading:6109660-Sheep,
pubmed-meshheading:6109660-Uterus
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pubmed:year |
1980
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pubmed:articleTitle |
Studies of circulation and acid-base balance in pregnant sheep: I. The effect of aminophylline infusion.
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pubmed:publicationType |
Journal Article
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