Linked Life Data

6109304

Source:http://linkedlifedata.com/resource/pubmed/id/6109304

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1180
pubmed:dateCreated
1981-3-17
pubmed:abstractText
Mouse cells stably transformed by simian virus 40 (SV40) contain viral DNA covalently integrated into their chromosomal DNA. We have used molecular cloning techniques to isolate and characterize the integrated viral DNA, together with the flanking cellular sequences, from several lines of transformed cells. We have identified in SV40-infected mouse cells a novel form of viral DNA, which we believe to be the precursor to the integrated DNA. The mRNAs transcribed from the integrated viral DNA templates have been characterized. Integrating the viral genome into the cellular chromosome can significantly alter its transcription pattern and in several cases the altered mRNAs encode novel forms of viral tumour antigen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0080-4649
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
210
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
437-50
pubmed:dateRevised
2007-4-30
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
The structure and expression of the integrated viral DNA in mouse cells transformed by simian virus 40.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't