Linked Life Data

6107918

Source:http://linkedlifedata.com/resource/pubmed/id/6107918

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1175
pubmed:dateCreated
1981-1-26
pubmed:abstractText
Aspects of the course of infection, growth and reproductive activity of Moniliformis were studied in adult male and female rats fed on isoenergetic purified diets containing various sugars. When rats were infected and fed on experimental diets containing either 3% glucose or 3% galactose for 5 weeks, very little growth of worms and no signs of reproduction were observed. In contrast, Moniliformis grew well and showed many signs of normal reproduction when the rats were fed on diets containing either 3% fructose or 3% mannose. The ability of the worms to grow and reproduce was not lost by maintaining them first for 5 weeks in rats fed on diets containing 3% glucose and 3% galactose. When the diets of such rats were changed to ones containing 3% starch and 3% fructose, respectively, for a further 5 weeks, the worms grew and normal reproduction occurred. Similar experiments were carried out in which groups of infected rats were fed for 5 weeks on diets containing gradually increasing amounts of glucose (6-36%). It was not until the rats were fed on diets containing 24% glucose that the mean dry mass of the worms approached that of worms from rats fed on the diet containing 3% fructose; no host diet was found to be as effective a supporter of worm growth as 3% mannose. Under no circumstances, not even when the host's diet contained 36%, was galactose found to be a suitable sugar for supporting the growth and reproduction of Moniliformis. Results consistent with those recorded for worms from rats fed on the diets containing monosaccharides were obtained when infected rats were fed for 5 weeks on diets containing 3% of various disaccharides. Considerable growth and reproduction of Moniliformis occurred when sucrose was included in the host's diet, but not when lactose, maltose or trehalose was present. Several of these observations may be related to the fact that different sugars are absorbed at different rates from the intestinal tract. It is suggested that all of a given sugar, when present in the diet at a low concentration, may be removed rapidly from the anterior part of the small intestine with the result that none will be available to the parasites. Significant amounts, however, of those sugars that are absorbed more slowly may reach the region of the intestine in which the parasite normally lives.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0080-4649
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
209
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-315
pubmed:dateRevised
2007-4-30
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
The growth of Moniliformis (Acanthocephala) in rats fed on various monosaccharides and disaccharides.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't