|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1980-9-23
|
|
pubmed:abstractText |
1. The specific activities of fatty acid synthetase, acetyl-CoA carboxylase and pyruvate dehydrogenase were measured in rat adipose-tissue extracts in pregnancy and lactation. Fatty acid synthetase specific activity correlates very closely with the rate of fatty acid synthesis, the enzyme specific activity decreasing after mid-pregnancy in a manner very similar to the rate of fatty acid synthesis. Acetyl-CoA carboxylase specific activity also decreases dramatically after mid-pregnancy. Initial pyruvate dehydrogenase specific activity shows a decrease between 2 days pre partum and 2 days post partum, but total enzyme activity shows no significant change in the same period. 2. Immunotitrations of fatty acid synthetase and pyruvate dehydrogenase activities were carried out; the titrations showed that the change in the fatty acid synthetase activity is due to a change in the enzyme amount; the amount of pyruvate dyhydrogenase does not change. Therefore the decrease in fatty acid biosynthesis in subcutaneous and parametrial adipose tissue in late pregnancy and early lactation is associated with a decrease in the amount of at least one of the enzymes involved in fatty acid biosynthesis. The correlation of these events with known hormonal changes is discussed.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-1156407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-1168420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-13084583,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-13212468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-14812083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-179467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-237534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-241300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-34543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4291570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4375962,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4401694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4415094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4462746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4633354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4638549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4686327,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4749458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-4975046,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-508293,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-5528598,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-5639924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-6012,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-6018,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-697748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6104955-999638
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0264-6021
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
186
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
937-44
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:6104955-Acetyl-CoA Carboxylase,
pubmed-meshheading:6104955-Adipose Tissue,
pubmed-meshheading:6104955-Animals,
pubmed-meshheading:6104955-Fatty Acid Synthetase Complex,
pubmed-meshheading:6104955-Fatty Acids,
pubmed-meshheading:6104955-Female,
pubmed-meshheading:6104955-Haplorhini,
pubmed-meshheading:6104955-Lactation,
pubmed-meshheading:6104955-Ligases,
pubmed-meshheading:6104955-Organ Size,
pubmed-meshheading:6104955-Pregnancy,
pubmed-meshheading:6104955-Pregnancy, Animal,
pubmed-meshheading:6104955-Proteins,
pubmed-meshheading:6104955-Pyruvate Dehydrogenase Complex
|
|
pubmed:year |
1980
|
|
pubmed:articleTitle |
Lipogenic enzymes in rat maternal adipose tissue in the perinatal period.
|
|
pubmed:publicationType |
Journal Article
|
