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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6211
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pubmed:dateCreated |
1980-6-25
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|
pubmed:abstractText |
The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study. Ketotifen in the higher dosage caused a slight reduction in salbutamol usage and a modest improvement in breathing in patients not already receiving inhaled corticosteroids. The drug was ineffective in patients receiving inhaled corticosteroids. Drowsiness was a troublesome effect causing withdrawal from treatment or reduction of dosage in seven patients while receiving ketotifen compared with only three while receiving placebo.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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|
pubmed:issn |
0007-1447
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
9
|
|
pubmed:volume |
280
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
360-1
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6102487-Adolescent,
pubmed-meshheading:6102487-Adrenal Cortex Hormones,
pubmed-meshheading:6102487-Adult,
pubmed-meshheading:6102487-Aged,
pubmed-meshheading:6102487-Albuterol,
pubmed-meshheading:6102487-Asthma,
pubmed-meshheading:6102487-Clinical Trials as Topic,
pubmed-meshheading:6102487-Double-Blind Method,
pubmed-meshheading:6102487-Drug Therapy, Combination,
pubmed-meshheading:6102487-Female,
pubmed-meshheading:6102487-Histamine H1 Antagonists,
pubmed-meshheading:6102487-Humans,
pubmed-meshheading:6102487-Ketotifen,
pubmed-meshheading:6102487-Male,
pubmed-meshheading:6102487-Middle Aged,
pubmed-meshheading:6102487-Piperidines,
pubmed-meshheading:6102487-Sleep Stages,
pubmed-meshheading:6102487-Thiophenes
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pubmed:year |
1980
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pubmed:articleTitle |
Ketotifen in adult asthma.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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