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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-3
|
pubmed:dateCreated |
1985-4-26
|
pubmed:abstractText |
Opioid receptor binding sites were analyzed in various segments of rat spinal cord. Mu and delta types were labelled with [3H]-DHM or [3H]-DAGO and [3H]-DADLE or [3H]-DSLET respectively. Kappa 1 (kappa) and kappa 2 (benzomorphan) binding sites were individually detected by the overall labeling of opioid binding sites with [3H]-etorphine followed by the elimination of binding to particular sites by the use of appropriate selective unlabelled ligands. Whereas lumbo sacral region contained mainly the kappa 2 site, thoracic membranes had a proportion of approximately 20% mu, 20% kappa 1 and 60% kappa 2 and cervical region contained much less kappa 2 sites (25% mu, 20% delta, 28% kappa 1 and 32% kappa 2).
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
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pubmed:issn |
0143-4179
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
113-6
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6099476-Animals,
pubmed-meshheading:6099476-Male,
pubmed-meshheading:6099476-Rats,
pubmed-meshheading:6099476-Rats, Inbred Strains,
pubmed-meshheading:6099476-Receptors, Opioid,
pubmed-meshheading:6099476-Receptors, Opioid, delta,
pubmed-meshheading:6099476-Receptors, Opioid, kappa,
pubmed-meshheading:6099476-Receptors, Opioid, mu,
pubmed-meshheading:6099476-Spinal Cord,
pubmed-meshheading:6099476-Tissue Distribution
|
pubmed:year |
1984
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pubmed:articleTitle |
Opioid binding sites in different levels of rat spinal cord.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
In Vitro
|