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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1985-4-29
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pubmed:abstractText |
The follow-up is presented for 13 patients with cervical intraepithelial neoplasia (CIN) grade II-III and vulvar intraepithelial neoplasia (VIN) grade III associated with papilloma virus infection, treated with human fibroblast interferon. Treatment consisted of 2-3 X 10(6) IU interferon per day injected intra- and peri-lesionally for five days per week for 2-3 weeks, with or without a cream topically applied at the dose of 1.2 X 10(6) IU/day X five days. Among the 13 patients with CIN and VIN, 7 complete (54%) and 2 partial regressions were observed. The duration of response appeared to be between 2 and 14 months. Fever, chills and fatigue were the tolerable side-effects. Our results indicate that treatment with interferon is active against CIN and VIN associated with papilloma virus infection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0250-0868
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
523-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6099344-Adult,
pubmed-meshheading:6099344-Animals,
pubmed-meshheading:6099344-Condylomata Acuminata,
pubmed-meshheading:6099344-Female,
pubmed-meshheading:6099344-Humans,
pubmed-meshheading:6099344-Immunotherapy,
pubmed-meshheading:6099344-Interferon Type I,
pubmed-meshheading:6099344-Middle Aged,
pubmed-meshheading:6099344-Papillomaviridae,
pubmed-meshheading:6099344-Tumor Virus Infections,
pubmed-meshheading:6099344-Uterine Cervical Neoplasms,
pubmed-meshheading:6099344-Vulvar Neoplasms
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pubmed:year |
1984
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pubmed:articleTitle |
Human fibroblast interferon in cervical and vulvar intraepithelial neoplasia associated with papilloma virus infection.
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pubmed:publicationType |
Journal Article
|