Linked Life Data

6098583

Source:http://linkedlifedata.com/resource/pubmed/id/6098583

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-3-25
pubmed:abstractText
In trials performed in Brazil, England and Germany, 765 pigs were challenged at one, three to four or 17 weeks after vaccination and their sera were titrated by macrocolour, microcolour or microcytopathic effects neutralization tests. Using O1 virus strains and challenge intervals of three to four weeks, significant correlations (P less than 0.01) were demonstrated between protection and serum neutralizing titres although the titres corresponding to given levels of protection varied with the titration method employed. The protective capacity of antiserum was confirmed by passive antibody transfer experiments. Retrospective analysis of 49 challenge tests showed that when the macrocolour test was employed, a group mean (n = 8) serum titre of 1.74 log10 SN50 corresponded with five out of eight (or more) protected from challenge in 92% of cases. The possibility of using serum titres as an alternative to challenge for oil emulsion vaccine potency tests is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0092-1157
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
379-89
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The relationship between serum antibody titres and protection from foot and mouth disease in pigs after oil emulsion vaccination.
pubmed:publicationType
Journal Article, Comparative Study