Linked Life Data

6096295

Source:http://linkedlifedata.com/resource/pubmed/id/6096295

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-1-28
pubmed:abstractText
In the presence of tunicamycin (TM), an antibiotic which inhibits glycosylation, Junin virus-infected cells released 70% as much virus as control cultures, as measured by [35S]-methionine appearing in a sucrose gradient virus particle fraction. In this same fraction, the incorporation of [14C]-glucosamine was inhibited 85% by TM, accompanied by a dramatic decrease in the envelope glycoprotein, Gp38, and a marked decrease in virus infectivity. These results indicate that the presence of Gp38 on the viral surface is essential for viral infectivity. In contrast, maturation and release of virus particles do not seem to be affected by the absence of Gp38 from the viral envelope.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5526
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Replication of Junin virus in the presence of tunicamycin.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't