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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
22
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pubmed:dateCreated |
1985-1-9
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pubmed:databankReference |
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pubmed:abstractText |
We have cloned a human V lambda cDNA sequence from an Ig lambda-producing human Burkitt lymphoma cell line (BL2) by taking advantage of a cloned constant region gene as a primer for cDNA synthesis instead of an oligo(dT) primer. The amino acid sequence deduced from the nucleotide sequence of V lambda clones is highly related to that of the NEW V lambda protein of subgroup I. Southern blot hybridization of human DNAs with the V lambda I probe showed at least 12 hybridizing V lambda fragments. These fragments are amplified in K562 cells which derive from a case of chronic myelogenous leukemia and contain an amplified c-abl oncogene and amplified C lambda sequences.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-100225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-103002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-103630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-111144,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-114999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-115000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-1195397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-232686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-265521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-4177823,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-418414,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6219389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6267606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6273747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6300689,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6306474,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6308652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6325541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6325542,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6417658,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6580644,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6775818,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6791160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6795508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6802926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6804942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-6812058,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-9732746,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6095199-99815
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8407-14
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6095199-Amino Acid Sequence,
pubmed-meshheading:6095199-Base Sequence,
pubmed-meshheading:6095199-Burkitt Lymphoma,
pubmed-meshheading:6095199-Cell Line,
pubmed-meshheading:6095199-Cloning, Molecular,
pubmed-meshheading:6095199-DNA,
pubmed-meshheading:6095199-DNA Restriction Enzymes,
pubmed-meshheading:6095199-Humans,
pubmed-meshheading:6095199-Immunoglobulin Light Chains,
pubmed-meshheading:6095199-Immunoglobulin Variable Region,
pubmed-meshheading:6095199-Immunoglobulin lambda-Chains,
pubmed-meshheading:6095199-Nucleic Acid Hybridization
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pubmed:year |
1984
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pubmed:articleTitle |
Molecular cloning of a human immunoglobulin lambda chain variable sequence.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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