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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
1984-12-28
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pubmed:abstractText |
We have used a cDNA clone for human apolipoprotein CII (apo CII) to detect a common DNA polymorphism with the enzyme TaqI. This polymorphism is probably caused by a single base change approximately 2000 base-pairs from the 3' end of the structural gene. In the normal population (n = 90) the frequency of the less common allele is approximately 0.44. No significant differences were observed in the allele frequency in individuals with type IIa, IIb, III, IV and V lipoprotein patterns. There does not seem to be any population association between the TaqI polymorphism and factors that predispose an individual to hyperlipidaemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0735-1313
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
463-71
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pubmed:dateRevised |
2008-8-29
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pubmed:meshHeading |
pubmed-meshheading:6094958-Adult,
pubmed-meshheading:6094958-Alleles,
pubmed-meshheading:6094958-Apolipoprotein C-II,
pubmed-meshheading:6094958-Apolipoproteins C,
pubmed-meshheading:6094958-Chromosome Mapping,
pubmed-meshheading:6094958-DNA,
pubmed-meshheading:6094958-DNA Restriction Enzymes,
pubmed-meshheading:6094958-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:6094958-Female,
pubmed-meshheading:6094958-Gene Frequency,
pubmed-meshheading:6094958-Genes,
pubmed-meshheading:6094958-Humans,
pubmed-meshheading:6094958-Hyperlipidemias,
pubmed-meshheading:6094958-Male,
pubmed-meshheading:6094958-Polymorphism, Genetic
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pubmed:year |
1983
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pubmed:articleTitle |
A DNA polymorphism adjacent to the human apolipoprotein CII gene.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
