|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1984-12-14
|
|
pubmed:abstractText |
Muscarinic-receptor stimulation by 0.1 mM-carbachol in longitudinal muscle of the guinea-pig ileum increases the incorporation of [3H]inositol into inositol-containing phospholipid. This effect was blocked by 16 microM-atropine. After 60 min incubation, carbachol increased the accumulation of total inositol phosphates 20-fold in the presence of 10 mM-Li+. Less than 20% of the total inositol phosphate corresponded to inositol 1-phosphate by ion-exchange chromatography, whereas of the remainder about two-thirds corresponded to inositol bisphosphate and one third to inositol trisphosphate. It is concluded that stimulation of muscarinic receptors in guinea-pig ileum enhances breakdown of polyphosphoinositides, suggesting that this may be a primary event associated with Ca2+ mobilization in the guinea-pig ileum.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-1267780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-13671378,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-13707646,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-14190470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-164246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-182125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-212082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-4344642,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-4723547,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6121338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6126885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6184051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6264039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6275838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6290478,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6296123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6297737,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6301436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6304096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6309146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6309153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6309155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6318733,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6320795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6323902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6324749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-6325442,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-7150264,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-7165867,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6093776-7284681
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0264-6021
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
223
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
527-31
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:6093776-Animals,
pubmed-meshheading:6093776-Atropine,
pubmed-meshheading:6093776-Carbachol,
pubmed-meshheading:6093776-Female,
pubmed-meshheading:6093776-Guinea Pigs,
pubmed-meshheading:6093776-Inositol,
pubmed-meshheading:6093776-Lithium,
pubmed-meshheading:6093776-Muscle, Smooth,
pubmed-meshheading:6093776-Phosphatidylinositol Phosphates,
pubmed-meshheading:6093776-Phosphatidylinositols,
pubmed-meshheading:6093776-Phospholipids,
pubmed-meshheading:6093776-Receptors, Muscarinic,
pubmed-meshheading:6093776-Stimulation, Chemical
|
|
pubmed:year |
1984
|
|
pubmed:articleTitle |
Muscarinic-receptor stimulation enhances polyphosphoinositide breakdown in guinea-pig ileum smooth muscle.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
