Linked Life Data

6092192

Source:http://linkedlifedata.com/resource/pubmed/id/6092192

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1984-12-20
pubmed:abstractText
Fifty lots of immune serum globulin prepared by four United States manufacturers between 1944 and 1977 were tested for the presence and titer of antibody to the hepatitis B virus-associated delta-agent. Anti-delta was detected in 28 of the 50 lots (56%) of immune serum globulin at titers ranging from 1:10 to 1:400. Anti-delta was present in 75% (6 of 8) of lots produced between 1962 and 1965, in 77% (17 of 21) produced between 1967 and 1970, in 45% (5 of 11) produced between 1971 and 1972 and in none (0 of 9) produced since 1973. A single lot of globulin prepared from plasma that was collected in 1944 from United States Army soldiers also contained detectable anti-delta. These data indicate that delta-infection has been occurring among hepatitis B surface antigen (HBsAg) carriers in the United States since the 1940s. The decrease in prevalence of anti-delta in immune serum globulin lots coincided with the start of routine HBsAg screening of blood and plasma. The elimination of HBsAg-positive units from plasma pools has reduced levels of HBsAg and anti-delta and should have decreased the risk of transmission of both type B hepatitis and delta-hepatitis by plasma products.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1213-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Antibody to the hepatitis B virus-associated delta-agent in immune serum globulins.
pubmed:publicationType
Journal Article, Comparative Study