Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1984-12-18
pubmed:abstractText
Competitive swimmers were followed over a 2-year period when they trained at different levels of exercise which coincided with distinct changes in their menstrual history. Oligomenorrhea was identified in 5 of 13 of these athletes when they swam approximately 100,000 yards per week. Weight and percentage of body fat were not significantly different between the period of oligomenorrhea and regular menstrual function (P = 0.24). Mean and median levels of luteinizing hormone, follicle-stimulating hormone, prolactin, and 17beta-estradiol were decreased and catechol estrogens and beta-endorphins were increased in serum during the strenuous, when compared with the moderate, training period. The serum levels of the steroid and protein hormones were similar to those of normal cycling, nonexercising control subjects during moderate exercise (60,000 yards per week). The significant differences between beta-endorphins and catechol estrogens during periods of strenuous exercise suggest an explanation for oligomenorrhea in female athletes. These hormonal changes result in hypothalamic anovulation, which appears to be reversible, because the hormone levels and menstrual cycles return to normal when the exercise is reduced.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0015-0282
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
690-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:6092153-Adolescent, pubmed-meshheading:6092153-Adult, pubmed-meshheading:6092153-Body Composition, pubmed-meshheading:6092153-Body Weight, pubmed-meshheading:6092153-Endorphins, pubmed-meshheading:6092153-Estradiol, pubmed-meshheading:6092153-Estrogens, Catechol, pubmed-meshheading:6092153-Female, pubmed-meshheading:6092153-Follicle Stimulating Hormone, pubmed-meshheading:6092153-Humans, pubmed-meshheading:6092153-Hypothalamo-Hypophyseal System, pubmed-meshheading:6092153-Luteinizing Hormone, pubmed-meshheading:6092153-Menstruation Disturbances, pubmed-meshheading:6092153-Oligomenorrhea, pubmed-meshheading:6092153-Physical Exertion, pubmed-meshheading:6092153-Prolactin, pubmed-meshheading:6092153-Sports Medicine, pubmed-meshheading:6092153-Swimming, pubmed-meshheading:6092153-beta-Endorphin
pubmed:year
1984
pubmed:articleTitle
The role of beta-endorphins and catechol estrogens on the hypothalamic-pituitary axis in female athletes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.