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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-12-12
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pubmed:abstractText |
Data are presented for sequence-specific chromatin-loop organization in histone-depleted nuclei from Drosophila melanogaster Kc cells. We find one loop for each of the tandemly repeated histone gene clusters. The attachment site is localized in the A + T rich H1-H3 spacer on a 657 bp fragment. In the cluster of the hsp70 heat-shock genes, in both control and heat-shocked cells, we find two attachment sites in close proximity upstream of regulatory elements. The transcribed sequences are not associated with the nuclear scaffold in control or in heat-shocked cells. A family of attachment sites related by hybridization to those of the hsp70 genes was discovered.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0092-8674
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
223-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6091913-Animals,
pubmed-meshheading:6091913-Cell Line,
pubmed-meshheading:6091913-Cell Nucleus,
pubmed-meshheading:6091913-Chromatin,
pubmed-meshheading:6091913-DNA,
pubmed-meshheading:6091913-DNA Restriction Enzymes,
pubmed-meshheading:6091913-Drosophila melanogaster,
pubmed-meshheading:6091913-Genes,
pubmed-meshheading:6091913-Histones
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pubmed:year |
1984
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pubmed:articleTitle |
Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|