Linked Life Data

6091847

Source:http://linkedlifedata.com/resource/pubmed/id/6091847

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-12-19
pubmed:abstractText
Thyrotropin-releasing hormone (TRH) is unevenly distributed throughout the rat central nervous system including spinal cord, where exogenous TRH elicits profound pharmacological effects. [Pro-3H]TRH binds to 30,000 g pellet fraction from the spinal cord saturably, reversibly, and with high affinity (apparent Kd = 24-25 nM). This binding is displaced by TRH and related biologically active, but not inactive, peptides. TRH binding is evenly distributed throughout the rat spinal cord. Characteristics of this binding suggest an association with a physiologically relevant TRH receptor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
311
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Thyrotropin-releasing hormone (TRH): apparent receptor binding in rat spinal cord.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.