Linked Life Data

6091220

Source:http://linkedlifedata.com/resource/pubmed/id/6091220

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-11-5
pubmed:abstractText
Since more than fifteen years ago, the occurrence of Cytomegalovirus (CMV) infections in transfused patients has incriminated blood as a potential vehicle for CMV transmission, resulting in post-transfusion mononucleosis (PTM). Although only Diosi and al. (1969) reported viraemia in two of 35 asymptomatic blood donors, CMV was not recovered from any leukocyte specimen of numerous healthy blood bank donors, assayed by cocultivation of undisrupted buffy coat with a virus sensitive monolayer of human fibroblasts. Nevertheless numerous experimental studies have shown that CMV might persist in very low titer or in a latent state in mononuclear leukocytes in monocytes and macrophages and in lymphocytes. A better knowledge of the site an mechanisms of latency should help to control CMV transmission by fresh and bank blood or transfusion of viable leukocytes.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0338-4535
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
295-300
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
[Physiopathology of cytomegalovirus infections].
pubmed:publicationType
Journal Article, English Abstract