rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5987
|
pubmed:dateCreated |
1984-11-21
|
pubmed:databankReference |
|
pubmed:abstractText |
We have purified the human T-cell growth factor (interleukin-2) receptor and have cloned, sequenced and expressed cDNAs corresponding to this receptor. We identify one gene, but two interleukin-2 receptor mRNAs which differ in their polyadenylation signals. We have isolated an additional cDNA that may correspond to an alternatively spliced mRNA that lacks a 216 base segment and appears to encode an altered membrane protein which cannot bind interleukin-2.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0028-0836
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
311
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
|
pubmed:pagination |
626-31
|
pubmed:dateRevised |
2005-11-17
|
pubmed:meshHeading |
pubmed-meshheading:6090948-Amino Acid Sequence,
pubmed-meshheading:6090948-Base Sequence,
pubmed-meshheading:6090948-Cloning, Molecular,
pubmed-meshheading:6090948-DNA,
pubmed-meshheading:6090948-Deltaretrovirus,
pubmed-meshheading:6090948-Genes,
pubmed-meshheading:6090948-Genes, Viral,
pubmed-meshheading:6090948-Humans,
pubmed-meshheading:6090948-Nucleic Acid Hybridization,
pubmed-meshheading:6090948-Protein Biosynthesis,
pubmed-meshheading:6090948-RNA, Messenger,
pubmed-meshheading:6090948-Receptors, Antigen, T-Cell,
pubmed-meshheading:6090948-Receptors, Immunologic,
pubmed-meshheading:6090948-Receptors, Interleukin-2
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pubmed:articleTitle |
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.
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pubmed:publicationType |
Journal Article
|