Linked Life Data

6089348

Source:http://linkedlifedata.com/resource/pubmed/id/6089348

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4669
pubmed:dateCreated
1984-10-17
pubmed:abstractText
Antibodies specific for human T-cell leukemia-lymphoma virus type I (HTLV-I) were demonstrated in serum samples from various groups of people in South Africa, Uganda, Ghana, Nigeria, Tunisia, and Egypt. The samples had been collected for other purposes and were presumably selected without bias toward clinical conditions associated with HTLV infections. Regional differences in antibody positivity were observed, indicating widely distributed loci of occurrence of HTLV on the African continent in people of both black and white ancestry. Two patients with high titers of antibody to HTLV-I had some signs of adult T-cell leukemia-lymphoma. In several groups a high frequency of false positive serum reactions was indicated when specific confirmation steps were included in the assay. Further characterization of these sera revealed highly elevated immunoglobulin levels, possibly due to polyclonal activation of immunoglobulin synthesis in these subjects. The possibility that related cross-reactive human retroviruses coexist in the same groups was not eliminated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
225
pubmed:owner
NLM
pubmed:authorsComplete
N
pubmed:pagination
1473-6
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Human T-cell leukemia virus (HTLV-I) antibodies in Africa.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't