Linked Life Data

6088604

Source:http://linkedlifedata.com/resource/pubmed/id/6088604

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
1984-9-21
pubmed:abstractText
Cyclic AMP (cAMP) has been postulated to regulate many of the events in the development of the eukaryotic social ameba Dictyostelium discoideum. The various suggested roles of cAMP could be tested were it possible to reversibly elevate cAMP levels in the organism. To this end we examined the effect of forskolin, which activates the adenylate cyclase of many eukaryotic organisms. We found, however, that the drug does not elevate cAMP levels in intact D. discoideum. In addition, it does not stimulate the adenylate cyclase in either its basal state or activated state.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0746-3898
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
297-303
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Forskolin does not activate cyclic AMP synthesis in Dictyostelium discoideum in vivo or in vitro.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.