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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1984-8-29
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pubmed:abstractText |
Adenosine receptors have been identified on brain cortical membranes and microvascular preparations. However, they have not been demonstrated on specific microvascular elements in isolation. 2-3H-chloroadenosine was used as a ligand to investigate the presence of adenosine receptors on isolated mouse cerebral smooth muscle membranes. The binding studies reveal the presence of a high affinity binding site with a Kd value of 33.3 nM and a maximal binding capacity (Bmax) of 283 fmol/mg protein. These findings demonstrate that there is an adenosine receptor on cerebral smooth muscle membranes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0039-2499
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
725-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6087502-2-Chloroadenosine,
pubmed-meshheading:6087502-Adenosine,
pubmed-meshheading:6087502-Animals,
pubmed-meshheading:6087502-Brain,
pubmed-meshheading:6087502-Cell Membrane,
pubmed-meshheading:6087502-Mice,
pubmed-meshheading:6087502-Microcirculation,
pubmed-meshheading:6087502-Muscle, Smooth, Vascular,
pubmed-meshheading:6087502-Receptors, Cell Surface,
pubmed-meshheading:6087502-Receptors, Purinergic,
pubmed-meshheading:6087502-Tritium
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pubmed:articleTitle |
Demonstration of adenosine receptors on mouse cerebral smooth muscle membranes.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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