Linked Life Data

6087366

Source:http://linkedlifedata.com/resource/pubmed/id/6087366

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-9-5
pubmed:abstractText
Leukotriene B4 (LTB4) synthesis and release by polymorphonuclear leukocytes (PMNL) from 17 male patients with type I diabetes mellitus was decreased (407.1 +/- 55.6 vs 709.4 +/- 62.7 ng/30 X 10(6) cells/10 min, mean +/- SE, p less than 0.001) as compared with 17 normal subjects matched for sex and age. There was an inverse correlation (r = -0.50, p less than 0.04) between LTB4 synthesis and plasma glucose concentration in the diabetic patients. The same correlation (r = -0.71, p less than 0.01) was observed in three diabetic patients studied weekly for one month. Because LTB4 is a potent chemoattractant and stimulates PMNL function, the defect in its synthesis may contribute to the predisposition to infections in the diabetic patient.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0262-1746
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
305-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Decreased leukotriene B4 synthesis by polymorphonuclear leukocytes from male patients with diabetes mellitus.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't