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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1984-9-7
|
| pubmed:abstractText |
N1 analogues of formycin B, with substituents at the 3 and 6 positions of the pyrazolo[4,3-d]pyrimidine moiety were synthesized by the direct SnCl4-catalyzed ribosylation method. The site of the glycosidic linkage and the anomeric configurations were established on the basis of X-ray crystallography, as well as 1H and 13C nuclear magnetic resonance spectroscopy. Preliminary results of the antiviral testing of these derivatives in vitro are described.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0022-2623
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
986-90
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6086926-Animals,
pubmed-meshheading:6086926-Antibiotics, Antineoplastic,
pubmed-meshheading:6086926-Antiviral Agents,
pubmed-meshheading:6086926-Cell Line,
pubmed-meshheading:6086926-Cercopithecus aethiops,
pubmed-meshheading:6086926-Formycins,
pubmed-meshheading:6086926-Magnetic Resonance Spectroscopy,
pubmed-meshheading:6086926-Models, Molecular,
pubmed-meshheading:6086926-Simplexvirus,
pubmed-meshheading:6086926-Viral Plaque Assay
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Pyrazolo[4,3-d]pyrimidine nucleosides. Synthesis and antiviral activity of 1-beta-D-ribofuranosyl-3-methyl-6-substituted-7H-pyrazolo[4,3-d]pyr imi din-7-ones.
|
| pubmed:publicationType |
Journal Article
|