rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-9-17
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pubmed:abstractText |
Human serum will inhibit the specific uptake of N-acetylglucosamine-terminated glycoproteins by isolated rat hepatic sinusoidal cells. The serum inhibitors are not glycoproteins that bind to the hepatic mannose/N-acetylglucosamine receptor but have the properties of lectins which bind to mannose/N-acetylglucosamine-terminated glycoproteins. They can be isolated from serum by affinity chromatography. The predominant lectin, with a molecular mass of less than 35 kDa, will inhibit the sinusoidal cell uptake of glycoproteins in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Asialoglycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Mannose-Binding Lectins,
http://linkedlifedata.com/resource/pubmed/chemical/Orosomucoid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/asialoorosomucoid,
http://linkedlifedata.com/resource/pubmed/chemical/mannose-N-acetylglucosamine receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-5793
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
173
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
63-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6086401-Animals,
pubmed-meshheading:6086401-Asialoglycoproteins,
pubmed-meshheading:6086401-Biological Transport,
pubmed-meshheading:6086401-Carbohydrate Sequence,
pubmed-meshheading:6086401-Cells, Cultured,
pubmed-meshheading:6086401-Glycoproteins,
pubmed-meshheading:6086401-Humans,
pubmed-meshheading:6086401-Kinetics,
pubmed-meshheading:6086401-Lectins,
pubmed-meshheading:6086401-Liver,
pubmed-meshheading:6086401-Male,
pubmed-meshheading:6086401-Mannose-Binding Lectins,
pubmed-meshheading:6086401-Orosomucoid,
pubmed-meshheading:6086401-Rats,
pubmed-meshheading:6086401-Receptors, Cell Surface,
pubmed-meshheading:6086401-Receptors, Immunologic
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pubmed:year |
1984
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pubmed:articleTitle |
Human serum contains a lectin which inhibits hepatic uptake of glycoproteins.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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