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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1984-9-12
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pubmed:abstractText |
In decerebrate cats a train of impulses in Ia afferents may lead to a sustained increase in excitability of alpha-motoneurones of homonymous and heteronymous muscles. It was previously suggested that this long-lasting excitability increase reflects a maintained synaptic input to the motoneurones from excitatory interneurones. With intracellular recording from motoneurones we here demonstrate that the sustained increase of alpha-motoneurone activity is due to an all-or-none plateau depolarization. This plateau can be induced by a short train of excitatory synaptic potentials or a brief, intracellularly injected depolarizing current pulse and is terminated by a short train of inhibitory synaptic potentials or a hyperpolarizing current pulse. It is concluded that maintained motor unit firing triggered by a brief train of impulses in Ia afferent reflects an intrinsic bistable behaviour of alpha-motoneurones.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0014-4819
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
391-4
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:6086378-Animals,
pubmed-meshheading:6086378-Cats,
pubmed-meshheading:6086378-Decerebrate State,
pubmed-meshheading:6086378-Interneurons,
pubmed-meshheading:6086378-Motor Neurons,
pubmed-meshheading:6086378-Neuromuscular Junction,
pubmed-meshheading:6086378-Serotonin,
pubmed-meshheading:6086378-Synaptic Transmission
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pubmed:year |
1984
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pubmed:articleTitle |
Intrinsic membrane properties causing a bistable behaviour of alpha-motoneurones.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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