Linked Life Data

6083799

Source:http://linkedlifedata.com/resource/pubmed/id/6083799

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1985-3-5
pubmed:abstractText
The effect of cigarette smoking during pregnancy on serum alpha-fetoprotein (AFP) levels was studied in 1925 consecutive women at 16-18 weeks gestation who subsequently had liveborn singleton infants. Cotinine and AFP were measured in sera in all the women and answers to a smoking questionnaire were analysed in 894. Cotinine, a metabolic derivative of nicotine, serves as an objective measure of the average daily absorption of smoking products because of its relatively long half-life. Infants born to women who smoked were, on average, 198 g lighter than those born to non-smokers, even though maternal weights were comparable. Whether analysed by self-reporting or by serum cotinine, cigarette smoking had no measurable effect on serum AFP levels.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Alpha Fetoproteins, http://linkedlifedata.com/resource/pubmed/keyword/BLOOD PROTEINS, http://linkedlifedata.com/resource/pubmed/keyword/Behavior, http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research, http://linkedlifedata.com/resource/pubmed/keyword/Hemic System, http://linkedlifedata.com/resource/pubmed/keyword/PROTEINS, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology, http://linkedlifedata.com/resource/pubmed/keyword/SMOKING, http://linkedlifedata.com/resource/pubmed/keyword/Social Behavior
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0306-5456
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1188-91
pubmed:dateRevised
2006-11-15
pubmed:otherAbstract
PIP: The effects of cigarette smoking during pregnancy on serum alpha-fetoprotein (AFP) levels was assessed in 1925 consecutive women at 16-18 weeks, gestation who subsequently delivered a liveborn singleton infant. Cotinine and AFP were measured in sera in all study subjects and answers to a smoking questionnaire were analyzed in 894 subjects. Mean serum AFP levels for the 308 self-reported smokers and the 586 nonsmokers were similar at all 3 gestational weeks. When analyzed by cotinine levels, cigarette smoking again had no measurable effect on serum AFP levels. However, infants born to women who smoked were an average of 198 gm lighter than those born to nonsmokers. The finding that cigarette smoking during pregnancy does not influence serum AFP levels differs from that reported in an earlier study, despite the fact that women in both studies had similar median body weights. It is concluded that, unless data to the contrary appear, meternal smoking habits should not be part of the interpretive process for maternal serum AFP levels.
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Does smoking influence serum alpha-fetoprotein levels in mid-trimester pregnancies?
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't