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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1978-4-26
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pubmed:abstractText |
Seventy-nine high-risk children were immunized with either commercial, bivalent, split-product influenza A vaccine or purified hemagglutinin-neuraminidase bivalent influenza A vaccine, and 78 of these subjects were immunized with commercial, monovalent, influenza B split-product vaccine. The reactogenicity of all three vaccines was low, and there were no severe reactions. Twenty-nine subjects who received hemagglutinin-neuraminidase vaccine as their initial dose and commercial split-product vaccine as a booster dose had significantly lower antibody responses to influenza A/New Jersey/76 virus than subjects who received two doses of commercial split-product vaccine. The responses of the two groups to influenza A/Victoria/75 virus were comparable. Twenty-four subjects with malignancy who were receiving chemotherapy were compared with a group of subjects matched for age and vaccine preparation. Patients with cancer had significantly lower antibody responses to A/New Jersey/76 virus than patients without cancer. The ultimate responses of patients with cancer to A/Victoria/75 and B/Hong Kong/72 viruses were comparable to those of other patients, but early responses were lower.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
136 Suppl
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S672-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:606790-Adolescent,
pubmed-meshheading:606790-Adult,
pubmed-meshheading:606790-Antibodies, Viral,
pubmed-meshheading:606790-Child,
pubmed-meshheading:606790-Child, Preschool,
pubmed-meshheading:606790-Chronic Disease,
pubmed-meshheading:606790-Diabetes Mellitus,
pubmed-meshheading:606790-Female,
pubmed-meshheading:606790-Heart Diseases,
pubmed-meshheading:606790-Humans,
pubmed-meshheading:606790-Immunologic Deficiency Syndromes,
pubmed-meshheading:606790-Influenza A virus,
pubmed-meshheading:606790-Influenza Vaccines,
pubmed-meshheading:606790-Kidney Diseases,
pubmed-meshheading:606790-Lung Diseases,
pubmed-meshheading:606790-Male,
pubmed-meshheading:606790-Neoplasms,
pubmed-meshheading:606790-Neuromuscular Diseases
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pubmed:year |
1977
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pubmed:articleTitle |
Reactogenicity and immunogenicity of bivalent influenza A and monovalent influenza B virus vaccines in high-risk children.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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