Linked Life Data

604367

Source:http://linkedlifedata.com/resource/pubmed/id/604367

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1978-4-17
pubmed:abstractText
Ultrastructural changes in specimens removed from Bowen's diseased genital areas of five patients are described, and a comparison is made with the tissue from the surrounding normal skin. Electron microscopic findings in Bowen's disease include an advanced dyskeratosis, acantholysis due to dissolution of desmosomal-tonofilament complexes, enlarged nuclei and nucleoli, increased polysome populations, mitochondrial alterations and nuclear inclusions. The basement membrane remains intact. Occasionally, atypical cells are undergoing cytolysis and are engulfed and phagocytized by the neighboring keratinocytes (apoptosis). The normal epithelium at the periphery of the lesion exhibits only a minimal degree of ultrastructural change.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0303-6987
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
266-74
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Bowen's disease of genital areas. An ultrastructural study.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.