Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1978-3-21
pubmed:abstractText
HBV has been shown to be responsible for a broad spectrum of disease in infants although most are asymptomatic carriers with mild transaminase elevation and unresolved hepatitis on liver biopsy. Maternal-infant transmission is responsible for most infections. Blood product infusion should become less significant. Acute maternal hepatitis in the perinatal period results in asymptomatic infant infections at rates far exceeding transmission from asymptomatic carrier mothers. Carrier mothers with the e-antigen or HBV-associated DNA polymerase transmit infection more readily than do carrier mothers without these HBV markers. The presence of maternal anti-e may be protective. Intrapartum and postpartum transmission occurs more often than transplacental infection. For this reason attempts at prophylaxis with immune serum globulin administered in the newborn period should be further evaluated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-3101
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
455-63
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The infant and hepatitis B virus infection.
pubmed:publicationType
Journal Article