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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1976-9-1
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pubmed:abstractText |
Purified protein derivative from Mycobacterium bovis was separated into 6 fractions by electrophoresis at 1500 V/40 mA in pH 4.2 acetic acid-pyridine buffer. Further purification of one of the fractions on Sephadex G 25 column and by acid hydrolysis yielded antigen "PS" eliciting tuberculin reaction only in animals vaccinated with M. bovis BCG but not in those sensitized with M. avium and some fast-growing mycobacteria. The specificity of antigen "PS" was confirmed in vitro: the antigen induced blastic transformation only in lymphocytes of guinea pigs sensitized with M. bovis BCG.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-6187
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
23-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:59518-Animals,
pubmed-meshheading:59518-Cattle,
pubmed-meshheading:59518-Chemical Fractionation,
pubmed-meshheading:59518-Epitopes,
pubmed-meshheading:59518-Guinea Pigs,
pubmed-meshheading:59518-Lymphocyte Activation,
pubmed-meshheading:59518-Mycobacterium avium,
pubmed-meshheading:59518-Mycobacterium bovis,
pubmed-meshheading:59518-Tuberculin,
pubmed-meshheading:59518-Tuberculin Test,
pubmed-meshheading:59518-Tuberculosis, Bovine
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pubmed:year |
1976
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pubmed:articleTitle |
Specificity of antigenic fractions of tuberculin.
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pubmed:publicationType |
Journal Article
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