Linked Life Data

591537

Source:http://linkedlifedata.com/resource/pubmed/id/591537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1978-2-18
pubmed:abstractText
Unilateral denervation of the hind limb in a group of adult rats prelabeled with radioactive proline induced a significant turnover of collagen in tendons, ligaments, menisci, and bones. After two or three months of disuse, there were significant losses (15 to 29 per cent) of old collagen from the four structures studied. Dilution of the radioactivity of the old collagen with new collagen involved partial to complete replacement of 3 to 20 per cent. The incomplete replacement of destroyed collagen with new collagen resulted in a net decrease of collagen mass ranging from 5 to 14 per cent. A significant turnover of collagen in two-year-old rats that showed little loss in collagen mass means that the new collagen produced would have fewer cross-links and would probably be weaker than the old, mature collagen.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-9355
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1065-7
pubmed:dateRevised
2010-10-25
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Turnover of collagen in the adult rat after denervation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.